Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 2.497


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMARCA1hg19_v1_chrX_-_128657381_128657436-0.732.5e-06Click!
SMARCC2hg19_v1_chr12_-_56583244_56583300-0.336.9e-02Click!
NCOR2hg19_v1_chr12_-_125052009_125052141-0.271.3e-01Click!
DMAP1hg19_v1_chr1_+_44679111_44679175-0.212.5e-01Click!
NCOR1hg19_v1_chr17_-_15973760_159738120.192.9e-01Click!
SMARCA5hg19_v1_chr4_+_144434555_1444349020.029.2e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_78200828 11.227 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr7_-_115670828 10.795 NM_001018058
NM_012252
TFEC

transcription factor EC

chr6_-_108145507 9.890 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr11_+_60869929 9.792 NM_014207
CD5
CD5 molecule
chrX_+_123480131 9.458 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr1_+_198608216 8.572 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_-_115670774 8.489 TFEC
transcription factor EC
chrX_-_131573638 8.447 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr1_-_150738232 8.440 CTSS
cathepsin S
chrX_+_37639246 8.307 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr1_+_32739711 8.255 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr7_+_106505876 8.108 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_-_167487701 7.715 NM_000734
NM_198053
CD247

CD247 molecule

chr17_-_29641087 7.686 EVI2B
ecotropic viral integration site 2B
chr7_-_115670811 7.580 TFEC
transcription factor EC
chrX_+_37639306 7.564 CYBB
cytochrome b-245, beta polypeptide
chr11_-_118213321 7.509 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr17_-_34207308 7.365 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr7_+_74188308 7.338 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr22_+_40322609 7.294 GRAP2
GRB2-related adaptor protein 2
chr4_-_48136245 7.199 NM_003328
TXK
TXK tyrosine kinase
chr1_+_167298280 7.036 NM_001198783
POU2F1
POU class 2 homeobox 1
chrX_-_30595883 6.949 NM_025159
CXorf21
chromosome X open reading frame 21
chr2_+_143886898 6.876 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr5_-_169724734 6.813 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_+_156607847 6.744 NM_005546
ITK
IL2-inducible T-cell kinase
chr1_-_150738292 6.688 NM_001199739
NM_004079
CTSS

cathepsin S

chr9_-_117692874 6.588 NM_001244
NM_001252290
TNFSF8

tumor necrosis factor (ligand) superfamily, member 8

chr1_-_150738255 6.541 CTSS
cathepsin S
chr5_-_138725544 6.499 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr11_-_104905849 6.439 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr2_+_143886969 6.415 ARHGAP15
Rho GTPase activating protein 15
chr12_-_10282680 6.379 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr9_+_127420690 6.273 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr5_-_169724817 6.083 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169724782 6.050 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr16_-_21663962 6.048 NM_005849
IGSF6
immunoglobulin superfamily, member 6
chr1_+_198608136 5.870 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr16_-_21663908 5.686 IGSF6
immunoglobulin superfamily, member 6
chr5_-_169724614 5.589 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_102595623 5.361 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr14_-_106725232 5.329 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr1_-_157789832 5.237 NM_001159397
NM_001159398
NM_052938
FCRL1


Fc receptor-like 1


chr3_+_111260925 5.198 NM_005816
NM_198196
CD96

CD96 molecule

chr4_+_40198526 5.084 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_159259503 5.071 NM_002001
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr1_+_32716839 5.046 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr12_-_121476770 5.041 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr11_-_104972147 5.037 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr1_+_192127591 4.939 NM_130782
RGS18
regulator of G-protein signaling 18
chr16_+_10971038 4.911 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr11_-_104916041 4.866 NM_001017534
NM_052889
CARD16

caspase recruitment domain family, member 16

chr1_+_158149736 4.855 NM_001766
CD1D
CD1d molecule
chr6_+_36665627 4.774 RAB44
RAB44, member RAS oncogene family
chr19_-_39826625 4.745 GMFG
glia maturation factor, gamma
chr12_-_15114495 4.735 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_167298382 4.678 POU2F1
POU class 2 homeobox 1
chr4_+_155484131 4.626 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr19_+_17516502 4.615 LOC100507535
uncharacterized LOC100507535
chr22_+_40297085 4.590 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr1_-_160832466 4.487 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr19_-_18508407 4.445 NM_145256
LRRC25
leucine rich repeat containing 25
chr3_+_121796695 4.437 NM_006889
NM_176892
CD86

CD86 molecule

chr11_-_8954534 4.396 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr1_+_247579457 4.358 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr1_+_84630575 4.356 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_+_149754245 4.328 NM_000566
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr1_-_93257950 4.319 NM_005665
EVI5
ecotropic viral integration site 5
chr11_-_128392061 4.283 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr2_+_103035148 4.230 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr19_-_10679328 4.195 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr4_-_153601085 4.164 NM_152680
TMEM154
transmembrane protein 154
chr19_-_39826676 4.101 NM_004877
GMFG
glia maturation factor, gamma
chr6_-_138189313 4.091


chr16_+_50308020 4.088 ADCY7
adenylate cyclase 7
chr17_-_29641068 4.077 EVI2B
ecotropic viral integration site 2B
chr1_-_161039745 4.012 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr14_-_23288912 3.997 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_75988765 3.957 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr18_+_22040592 3.893 NM_001143828
NM_001160166
NM_021624
HRH4


histamine receptor H4


chr15_+_89182038 3.889 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr7_-_96633608 3.830 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr1_-_161039703 3.821 ARHGAP30
Rho GTPase activating protein 30
chr14_+_75988838 3.734 BATF
basic leucine zipper transcription factor, ATF-like
chr1_+_15736387 3.724 NM_024329
EFHD2
EF-hand domain family, member D2
chr6_+_29691116 3.703 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr13_-_46756326 3.685 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_29641094 3.673 NM_006495
EVI2B
ecotropic viral integration site 2B
chr6_+_45296053 3.611 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr11_-_128391888 3.611 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr2_-_166650546 3.582 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_15736422 3.575 EFHD2
EF-hand domain family, member D2
chr7_+_37779995 3.520 NM_181791
GPR141
G protein-coupled receptor 141
chr6_-_24719286 3.520 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr22_+_23229959 3.501 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr4_-_155511838 3.497 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr1_+_9005921 3.479 NM_001215
CA6
carbonic anhydrase VI
chr10_-_11574273 3.472 NM_001080491
USP6NL
USP6 N-terminal like
chr16_+_12058963 3.464 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr6_-_128222175 3.423 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr18_-_30352841 3.415 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr3_+_187086167 3.387 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr11_+_124933197 3.349 SLC37A2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr21_+_43823970 3.322 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr7_+_28452143 3.307 NM_182898
CREB5
cAMP responsive element binding protein 5
chr14_-_107199126 3.294 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr13_-_74707913 3.249 NM_007249
KLF12
Kruppel-like factor 12
chr11_+_124933007 3.236 NM_001145290
NM_198277
SLC37A2

solute carrier family 37 (glycerol-3-phosphate transporter), member 2

chr14_-_25103365 3.228 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr4_+_36285643 3.181 NM_001170700
DTHD1
death domain containing 1
chr13_+_108921976 3.166 NM_001145645
NM_006573
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr2_-_166650770 3.143 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr18_+_72922725 3.135 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr16_-_28518131 3.112 NM_145659
IL27
interleukin 27
chr7_-_76829109 3.052 NM_006682
FGL2
fibrinogen-like 2
chr1_-_47695442 3.048 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr2_-_166650705 3.046 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr3_-_157221127 3.042 NM_001167911
NM_001167912
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr1_+_40862471 3.042 NM_001198980
SMAP2
small ArfGAP2
chr1_+_84630374 3.041 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_53601051 3.032 ITGB7
integrin, beta 7
chr1_+_84609987 3.018 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr22_+_40297183 3.010 GRAP2
GRB2-related adaptor protein 2
chr13_-_103719195 2.993 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chrX_+_12924738 2.947 NM_138636
TLR8
toll-like receptor 8
chr1_+_198608244 2.945 PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_+_6659356 2.942 XAF1
XIAP associated factor 1
chr3_-_3152057 2.936 NM_000564
NM_001243099
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
IL5RA






interleukin 5 receptor, alpha






chr2_-_161130151 2.925 RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_-_14816895 2.923 NM_031453
FAM107B
family with sequence similarity 107, member B
chr16_+_57023411 2.917 NLRC5
NLR family, CARD domain containing 5
chr22_-_23922376 2.905 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr1_+_113162449 2.780 CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr21_-_34185943 2.729 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_+_161676761 2.716 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr2_-_160472960 2.711 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr12_+_25205180 2.707 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr16_-_11350038 2.688 NM_003745
SOCS1
suppressor of cytokine signaling 1
chr6_+_31539875 2.687 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr14_-_106691698 2.681


chr1_-_200377262 2.660 ZNF281
zinc finger protein 281
chr1_+_113162074 2.635 NM_006135
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chrX_-_49121171 2.608 NM_001114377
NM_014009
FOXP3

forkhead box P3

chr1_+_113162421 2.567 CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_-_207095198 2.567 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_34417386 2.555 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr12_-_9885859 2.517 NM_001253748
NM_001253750
NM_172004
CLECL1


C-type lectin-like 1


chr1_+_158259558 2.505 NM_001765
CD1C
CD1c molecule
chr5_-_176738831 2.490 MXD3
MAX dimerization protein 3
chr1_+_113162456 2.489 CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_+_84630014 2.485 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr3_-_49851217 2.471 UBA7
ubiquitin-like modifier activating enzyme 7
chr4_-_40516567 2.465 RBM47
RNA binding motif protein 47
chr17_+_6659155 2.455 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr1_+_48688356 2.450 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr3_-_157221362 2.425 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr2_+_113885137 2.403 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr1_+_113217039 2.397 NM_001130079
NM_020963
MOV10

Mov10, Moloney leukemia virus 10, homolog (mouse)

chr5_-_41071404 2.322 NM_173489
HEATR7B2
HEAT repeat family member 7B2
chr19_-_10679620 2.313 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr15_-_45003513 2.310


chr7_-_92777657 2.283 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr3_-_195938256 2.269 NM_001039617
ZDHHC19
zinc finger, DHHC-type containing 19
chr4_-_122085475 2.268 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr17_-_80407601 2.267 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr1_+_948846 2.266 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr3_+_63953419 2.261 NM_001128149
ATXN7
ataxin 7
chr12_+_11802905 2.257 ETV6
ets variant 6
chr1_-_200377488 2.257 ZNF281
zinc finger protein 281
chr6_-_32908583 2.243 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_+_26365397 2.241 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr6_-_133035180 2.239 NM_004666
VNN1
vanin 1
chr6_-_149806116 2.235 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr12_+_11802726 2.233 NM_001987
ETV6
ets variant 6
chr15_+_80364902 2.218 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr17_+_7462064 2.215 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_54447660 2.207 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr3_+_45927995 2.204 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr6_+_26402464 2.204 NM_001145008
NM_001145009
NM_007048
NM_194441
BTN3A1



butyrophilin, subfamily 3, member A1



chr3_-_112693711 2.192 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr6_+_105404922 2.147 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr15_+_45003659 2.147 NM_004048
B2M
beta-2-microglobulin
chr16_-_50715240 2.136 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr5_-_149792276 2.129 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_+_5710926 2.122 TRIM22
tripartite motif containing 22
chr13_+_28712379 2.117 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr4_-_39523132 2.105 UGDH
UDP-glucose 6-dehydrogenase
chr13_-_26789062 2.103 RNF6
ring finger protein (C3H2C3 type) 6
chr17_-_47287935 2.083 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr12_-_53600999 2.077 NM_000889
ITGB7
integrin, beta 7
chr11_+_118754474 2.077 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr5_-_149465989 2.038 CSF1R
colony stimulating factor 1 receptor
chr9_+_5890801 2.024 NM_005511
MLANA
melan-A
chr1_-_120935943 1.998 NM_001004340
NM_001017986
NM_001244910
FCGR1A
FCGR1B


Fc fragment of IgG, high affinity Ia, receptor (CD64)
Fc fragment of IgG, high affinity Ib, receptor (CD64)


chr12_-_49319211 1.998 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chrX_-_19688991 1.975 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr3_-_167371288 1.973 NM_178824
WDR49
WD repeat domain 49
chr4_-_38806410 1.952 NM_003263
TLR1
toll-like receptor 1
chr2_+_182322265 1.948 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_-_169555624 1.939 F5
coagulation factor V (proaccelerin, labile factor)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.49 2.07e-33 GO:0002376 immune system process
5.45 1.18e-28 GO:0006955 immune response
4.35 6.02e-16 GO:0002682 regulation of immune system process
3.86 2.14e-14 GO:0006952 defense response
5.09 6.32e-14 GO:0050776 regulation of immune response
5.02 7.13e-11 GO:0045087 innate immune response
4.22 7.97e-09 GO:0002684 positive regulation of immune system process
5.62 1.05e-08 GO:0045321 leukocyte activation
4.96 5.70e-08 GO:0050778 positive regulation of immune response
5.82 3.13e-07 GO:0046649 lymphocyte activation
5.19 3.61e-07 GO:0002694 regulation of leukocyte activation
5.46 3.65e-07 GO:0051249 regulation of lymphocyte activation
7.55 4.12e-07 GO:0042110 T cell activation
2.18 6.46e-07 GO:0048583 regulation of response to stimulus
7.99 6.55e-07 GO:0002429 immune response-activating cell surface receptor signaling pathway
5.00 7.57e-07 GO:0050865 regulation of cell activation
5.81 9.06e-07 GO:0002696 positive regulation of leukocyte activation
1.50 1.02e-06 GO:0050896 response to stimulus
7.69 1.15e-06 GO:0002768 immune response-regulating cell surface receptor signaling pathway
5.71 1.21e-06 GO:0050867 positive regulation of cell activation
5.56 1.93e-06 GO:0019221 cytokine-mediated signaling pathway
5.91 1.95e-06 GO:0051251 positive regulation of lymphocyte activation
8.10 2.06e-06 GO:0050851 antigen receptor-mediated signaling pathway
3.55 2.47e-06 GO:0001775 cell activation
4.37 4.12e-06 GO:0034097 response to cytokine stimulus
6.42 4.65e-06 GO:0050870 positive regulation of T cell activation
1.38 1.03e-05 GO:0065007 biological regulation
5.01 1.08e-05 GO:0071345 cellular response to cytokine stimulus
1.40 1.33e-05 GO:0050789 regulation of biological process
8.61 1.49e-05 GO:0050852 T cell receptor signaling pathway
1.91 1.49e-05 GO:0006950 response to stress
5.86 1.79e-05 GO:0002697 regulation of immune effector process
9.54 1.97e-05 GO:0060337 type I interferon-mediated signaling pathway
9.54 1.97e-05 GO:0071357 cellular response to type I interferon
1.72 2.21e-05 GO:0007165 signal transduction
9.39 2.34e-05 GO:0034340 response to type I interferon
1.67 2.39e-05 GO:0023052 signaling
8.07 3.15e-05 GO:0034341 response to interferon-gamma
2.03 7.75e-05 GO:0007166 cell surface receptor linked signaling pathway
5.19 1.01e-04 GO:0050863 regulation of T cell activation
8.97 1.65e-04 GO:0050864 regulation of B cell activation
8.68 2.28e-04 GO:0060333 interferon-gamma-mediated signaling pathway
1.56 3.82e-04 GO:0051716 cellular response to stimulus
7.91 5.57e-04 GO:0071346 cellular response to interferon-gamma
4.30 6.08e-04 GO:0002253 activation of immune response
1.37 7.95e-04 GO:0050794 regulation of cellular process
3.27 8.58e-04 GO:0051707 response to other organism
4.72 8.65e-04 GO:0002757 immune response-activating signal transduction
8.65 9.66e-04 GO:0002706 regulation of lymphocyte mediated immunity
8.65 9.66e-04 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.51 9.91e-04 GO:0048584 positive regulation of response to stimulus
8.49 1.13e-03 GO:0002819 regulation of adaptive immune response
3.73 1.13e-03 GO:0002520 immune system development
3.58 1.14e-03 GO:0031347 regulation of defense response
4.61 1.16e-03 GO:0002764 immune response-regulating signaling pathway
7.17 1.42e-03 GO:0002699 positive regulation of immune effector process
6.23 1.75e-03 GO:0030098 lymphocyte differentiation
3.78 1.79e-03 GO:0001817 regulation of cytokine production
7.81 2.34e-03 GO:0030217 T cell differentiation
3.64 3.09e-03 GO:0006954 inflammatory response
7.34 4.01e-03 GO:0002703 regulation of leukocyte mediated immunity
30.73 4.48e-03 GO:0002676 regulation of chronic inflammatory response
1.67 5.37e-03 GO:0048518 positive regulation of biological process
2.84 5.72e-03 GO:0048585 negative regulation of response to stimulus
4.57 6.74e-03 GO:0009615 response to virus
3.60 6.79e-03 GO:0048534 hemopoietic or lymphoid organ development
2.80 7.14e-03 GO:0009607 response to biotic stimulus
7.97 7.47e-03 GO:0006968 cellular defense response
9.41 9.11e-03 GO:0045582 positive regulation of T cell differentiation
2.26 9.64e-03 GO:0051704 multi-organism process
8.56 1.76e-02 GO:0045621 positive regulation of lymphocyte differentiation
6.94 2.13e-02 GO:0031294 lymphocyte costimulation
6.94 2.13e-02 GO:0031295 T cell costimulation
4.77 2.35e-02 GO:0002521 leukocyte differentiation
2.18 2.73e-02 GO:0009611 response to wounding
5.17 2.77e-02 GO:0070663 regulation of leukocyte proliferation
2.88 2.92e-02 GO:0009968 negative regulation of signal transduction
7.69 3.64e-02 GO:0050688 regulation of defense response to virus
2.40 4.37e-02 GO:0071310 cellular response to organic substance

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.42 6.75e-03 GO:0043235 receptor complex
4.29 8.85e-03 GO:0009897 external side of plasma membrane
1.41 1.40e-02 GO:0005886 plasma membrane
1.41 1.52e-02 GO:0071944 cell periphery
23.05 3.35e-02 GO:0005577 fibrinogen complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
14.79 3.32e-08 GO:0003823 antigen binding
5.98 2.36e-04 GO:0019955 cytokine binding
1.17 3.70e-03 GO:0005488 binding
3.59 4.25e-02 GO:0005126 cytokine receptor binding